兔抗ADD1(Phospho-Ser726)多克隆抗体

Background:

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Applications:

WB, IHC, IF

Name of antibody:

ADD1 (Phospho-Ser726)

Immunogen:

Synthetic peptide of human ADD1 (Phospho-Ser726)

Full name:

adducin 1 (alpha) (Phospho-Ser726)

Synonyms：

ADDA

SwissProt:

P35611

IHC positive control:

Human lung carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

130 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200