兔抗BRAF(Phospho-Ser446)多克隆抗体

Background:

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

Applications:

WB

Name of antibody:

BRAF(Phospho-Ser446)

Immunogen:

Peptide sequence around phosphorylation site of Serine 446 (R-D-S(p)-S-D) derived from Human B-RAF.

Full name:

B-Raf proto-oncogene, serine/threonine kinase

Synonyms：

NS7; BRAF1; RAFB1; B-RAF1

SwissProt:

P15056

WB Predicted band size:

84 kDa

WB Positive control:

293 cells lysates treated with EGF

WB Recommended dilution:

500-1000